Molecular Formula | C17H15N7 |
Molar Mass | 317.36 |
Density | 1.42±0.1 g/cm3(Predicted) |
Boling Point | 590.9±58.0 °C(Predicted) |
Solubility | ≤1mg/ml in ethanol;20mg/ml in DMSO;20mg/ml in dimethyl formamide |
Appearance | crystalline solid |
pKa | 7.53±0.70(Predicted) |
biological activity | VLX600 is a novel iron-chelated inhibitor of oxidative phosphorylation (OXPHOS), the effect of radiotherapy on tumor spheroids is enhanced by synergistic action. VLX600 can exhibit enhanced cytotoxicity under conditions of nutrient deficiency. VLX600 can induce autophagy and mitochondrial inhibition and has anti-tumor activity. |
Target | Value |